Sunday, June 23, 2013

Militants kill 9 foreign tourists, 1 Pakistani

ISLAMABAD (AP) ? Islamic militants wearing police uniforms shot to death nine foreign tourists and one Pakistani before dawn Sunday as they were visiting one of the world's highest mountains in a remote area of northern Pakistan, officials said.

The foreigners who were killed included five Ukrainians, three Chinese and one Russian, said Pakistani Interior Minister Chaudhry Nisar Ali Khan. One Chinese tourist was wounded in the attack and was rescued, he said.

The local branch of the Taliban took responsibility for the killings, saying it was to avenge the death of a leader killed in a drone strike.

The shooting is likely to damage the country's struggling tourism industry. Pakistan's mountainous north ? considered until now relatively safe ? is one of the main attractions in a country beset with insurgency and other political instability.

The attack took place at the base camp of Nanga Parbat, the ninth highest mountain in the world at 8,126 meters (26,660 feet). Nanga Parbat is notoriously difficult to climb and is known as the "killer mountain" because of numerous mountaineering deaths in the past. It's unclear if the tourists were planning to climb the mountain or were just visiting the base camp, which is located in the Gilgit-Baltistan region of Pakistan.

The gunmen were wearing uniforms used by the Gilgit Scouts, a paramilitary police force that patrols the area, said the interior minister. The attackers abducted two local guides to find their way to the remote base camp. One of the guides was killed in the shooting, and the other has been detained and is being questioned, said Khan.

"The government will take all measures to ensure the safety of foreign tourists," said the interior minister in a speech in the National Assembly, which passed a resolution condemning the incident.

Pakistani Taliban spokesman Ahsanullah Ahsan claimed responsibility for the attack, saying their Jundul Hafsa group carried out the shooting as retaliation for the death of the Taliban's deputy leader, Waliur Rehman, in a U.S. drone attack on May 29.

"By killing foreigners, we wanted to give a message to the world to play their role in bringing an end to the drone attacks," Ahsan told The Associated Press by telephone from an undisclosed location.

The attackers beat up the Pakistanis who were accompanying the tourists, took their money and tied them up, said a senior local government official. They checked the identities of the Pakistanis and shot to death one of them, possibly because he was a minority Shiite Muslim, said the official, speaking on condition of anonymity because he was not authorized to talk to the media. Although Gilgit-Baltistan is a relatively peaceful area, it has experienced attacks by radical Sunni Muslims on Shiites in recent years.

The attackers took the money and passports from the foreigners and then gunned them down, said the official. It's unclear how the Chinese tourist who was rescued managed to avoid being killed.

Local police chief Barkat Ali said they first learned of the attack when one of the local guides called the police station around 1 a.m. on Sunday.

The Pakistani government condemned the shooting in a statement sent to reporters.

"The government of Pakistan expresses its deep sense of shock and grief on this brutal act of terrorism, and extends its sympathy to the families of the victims," said a statement issued by the Foreign Ministry. "Those who have committed this heinous crime seem to be attempting to disrupt the growing relations of Pakistan with China and other friendly countries."

Pakistan has very close ties with neighboring China and is very sensitive to an issue that could harm the relationship. Pakistani officials have reached out to representatives from China and Ukraine to convey their sympathies, the Foreign Ministry said.

Many foreign tourists stay away from Pakistan because of the perceived danger of visiting a country that is home to a large number of Islamic militant groups, such as the Taliban and al-Qaida, which mostly reside in the northwest near the Afghan border. But a relatively small number of intrepid foreigners visit Gilgit-Baltistan during the summer to marvel at the peaks of the Himalayan and Karakoram ranges, including K2, the second highest mountain in the world.

Syed Mehdi Shah, the chief minister of Gilgit-Baltistan, condemned the attack and expressed fear that it would seriously damage the region's tourism industry.

"A lot of tourists come to this area in the summer, and our local people work to earn money from these people," said Shah. "This will not only affect our area, but will adversely affect all of Pakistan."

Shah said authorities are still trying to get more information about exactly what happened to the tourists. The area where the attack occurred, Bunar Nala, is only accessible by foot or on horseback, and communications can be difficult, said Shah. Bunar Nala is on one of three routes to reach Nanga Parbat, he said.

The area has been cordoned off by police and paramilitary soldiers, and a military helicopter is searching the area, said Shah. The military plans to airlift the bodies of the foreign tourists to Islamabad, he said.

"God willing we will find the perpetrators of this tragic incident," said Shah.

The government suspended the top police chief in Gilgit-Baltistan following the attack and has ordered an inquiry into the incident, said Khan, the interior minister.

_____

Associated Press writer Rasool Dawar contributed to this report from Peshawar, Pakistan.

Source: http://news.yahoo.com/militants-kill-9-foreign-tourists-1-pakistani-083351537.html

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Thanks To A Six-Figure Purchase By Reputation Changer, Brand.com Is A Thing Now

brand logoMy boss Alexia Tsotsis is going to love this one. With a name like Reputation Changer, you can imagine that an online reputation management company would be stuck in the shadow of Reputation.com (which itself was formerly known as Reputation Defender). The solution? It's changing its name, and purchasing a memorable URL of its own ? Brand.com.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/rF8bHxYy1Mw/

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Saturday, June 22, 2013

Oil rebounds, remains above $95 a barrel

Oil prices staged a moderate rebound Friday, a day after their sharpest drop in more than seven months.

By early afternoon in Europe, benchmark oil for August delivery was up 41 cents to $95.55 a barrel in electronic trading on the New York Mercantile Exchange.

On Thursday, the expiring Nymex contract for July settlement sank $2.84, or 2.9 percent, to $95.40 a barrel. The sharp drop was precipitated by weak Chinese manufacturing data and signals that the U.S. central bank is preparing to scale back its stimulus policies.

Thursday's "events mean that oil shed all of the gains of the past two weeks, showing just how susceptible the oil market is to external influences," said a report from Commerzbank in Frankfurt. "There has after all been no change in the fundamentals since the beginning of the month."

Analysts said rising crude output combined with the Fed's signal that it would start tapering down its asset purchases this year have put downward pressure on oil prices. But Syria's civil war and Iran's pursuit of nuclear projects were risks that had the potential to disrupt energy markets and could cause prices to rise.

"The geopolitical premium must not be forgotten, and may not remain muted for long," said analysts at Credit Agricole CIB in Hong Kong.

On Wednesday, Fed chairman Ben Bernanke suggested that he was optimistic about the U.S. economy ? and that the Fed might start scaling back its massive $85 billion-a-month bond-buying program this year if conditions continue to improve. The Fed could end the program by the middle of next year, Bernanke said.

The Fed program has kept borrowing costs near historic lows for consumers and business. It has also helped boost the equities and energy markets.

Brent crude, a benchmark for many international oil varieties, was up 52 cents to $102.67. Brent plunged $3.97, or 3.7 percent, to end on Thursday at $102.94 a barrel on the ICE Futures exchange in London.

In other energy futures trading on the Nymex:

? Wholesale gasoline rose 1.57 cents to $2.7932 a gallon.

? Heating oil added 1.52 cents to $2.8882 per gallon.

? Natural gas advanced 1.3 cents to $3.89 per 1,000 cubic feet.

___

Pamela Sampson in Bangkok contributed to this report.

Source: http://news.yahoo.com/oil-rebounds-remains-above-95-barrel-053721966.html

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Trouble either way

Super Bowl XLVI - Media DayGetty Images

Thirteen years ago, Ravens linebacker Ray Lewis faced double murder charges in Atlanta.? Eventually, he pleaded guilty to obstruction of justice, with an agreement to testify against other defendants.? No one was convicted of the killings.

While Lewis avoided the far more serious crime, the NFL still fined Lewis $250,000 for his role in, as prosecutors have described such cases, kicking dirt in the eyes of the authorities.? If that?s the only charge prosecutors in Boston ever are able to pin on Patriots tight end Aaron Hernandez, either by guilty plea or through the introduction of proof beyond a reasonable doubt, Hernandez can count on an even stiffer sanction from the league office than the Lewis penalty.

Six years ago, Commissioner Roger Goodell overhauled the personal-conduct policy, expanding its reach and enhancing its penalties.? Since then, Goodell has shown a willingness to take swift and decisive action against players who violate it.? Pacman Jones received a one-year suspension despite never going to jail for any of his various legal entanglements at the NFL level.? Ben Roethlisberger received a six-game suspension (reduced to four) despite never even being arrested.? And the NFL indefinitely suspended Mike Vick the moment he was indicted for charges of dogfighting and gambling.

For Hernandez, the clearest apples-to-apples comparison comes from the cases of Leonard Little and Donte? Stallworth.? Both caused a death while driving drunk.? Little was suspended eight games by Commissioner Paul Tagliabue in 1999.? Stallworth received a full year from Goodell in 2009.

From Hernandez?s perspective, that formula would result in a fine of $500,000, if he pleads guilty to obstruction of justice.? We?ve got a feeling, based on Goodell?s history of imposing discipline for off-field misbehavior, that won?t happen.

Based on reports from ABC and FOX 25 in Boston, police believe Hernandez deliberately destroyed (or at least tried to destroy) electronic evidence that would likely help solve the question of who killed Odin Lloyd.? Goodell won?t react kindly to NFL players attempting so brazenly to prevent justice from being done, especially when ?justice? entails finding a murderer.? If Roethlisberger was suspended four games for being sued for sexual assault in Nevada and accused of another in Georgia despite never being arrested or charged, Hernandez could be in line for something like that or worse if he ultimately admits or is convicted of attempting to cover up a murder.

It gets far worse for Hernandez if he?s charged with murder.? Or if the NFL, through the in-house police force known as NFL Security, determines that he did it.? There?s no ?if it doesn?t fit you must acquit? in the Court of the Commissioner.? He remains, under the personal-conduct policy, the judge, jury, executioner, appeals court, and governor.? And while the bounty case proved that diligent, aggressive lawyering could force Goodell to bump the appeal to his more lenient predecessor, Goodell and company surely learned from that experience how to avoid creating evidence that could be used to undermine his perceived neutrality.

So, basically, Hernandez is likely looking at a suspension if obstruction of justice sticks.? If the NFL decides he did more than merely help cover things up, Hernandez may be gone from the game for a long time.

The more immediate question becomes whether the league and the Patriots will allow Hernandez to show up for training camp if the situation remains unresolved.? The NFL and the Cowboys have managed to keep defensive tackle Josh Brent at a distance while he prepares for a September 2013 trial in the DUI death of Cowboys linebacker Jerry Brown.? Look for the league and the Pats to finesse a similar outcome that would keep Hernandez from being a far bigger distraction than the player the Patriots signed only 10 days ago.

UPDATE 10:42 a.m. ET:? This item was based on multiple reports than arrest warrant has been issued for Hernandez, and that he will be charged with obstruction of justice.? The Boston Globe has since reported that no arrest warrant has been issued.

Source: http://profootballtalk.nbcsports.com/2013/06/21/even-with-only-obstruction-of-justice-charge-hernandez-faces-real-problems-at-work/related/

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Kim Kardashian Baby Photos: What Will North West Look Like?!

Source:

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People's Fest at Atlantic Station | Atlanta Food & Drink Blog ...

Source: http://clatl.com/omnivore/archives/2013/06/21/peoples-fest-at-atlantic-station

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Hey, North West, greetings from the Northwest

Pop culture

11 hours ago

Image: Kim Kardashian and Kanye West

Eric Ryan / Getty Images file

New parents Kim Kardashian and Kanye West.

Northwesterners are a proud lot. We actually like being 3,000 miles from everything. We like our music. We like the rain. We're not big on attention -- especially the kind that comes with a major celebrity couple naming their new baby after the region we call home.

Seattle, where this story is originating from, is hardly a backwoods outpost devoid of celebrity intrigue. We've got our own hip-hop royalty in Macklemore ... you know, the "Thrift Shop" guy. (Tired of that song? At least his album, which went gold in April, isn't called "Yeezus.") We've got memories of Elvis singing under the Space Needle and the Beatles fishing from a hotel window. Frasier Crane lived here and the "Grey's Anatomy" doctors worked here; so did Tom Hanks in that movie we don't need to name.

We were all a little "Sleepless" Thursday night when Twitter started pointing at us. Actually, Twitter started pointing at a little girl whose new name is North West. Her parents, rapper Kanye West and reality-er Kim Kardashian, bucked weeks of K-name rumors, it seemed, and went in a new direction. We wish they'd used a different kompass.

For a little girl who will likely grow up in Los Angeles and New York and Miami and Paris, being saddled with a soggy moniker will take some getting used to. Kind of like getting used to being the daughter of Kim Kardashian and Kanye West. Nori, as she'll reportedly be known, should be aware of some of the stereotypes associated with the Northwest, even if she never lives here.

Forget the coffee thing and the grunge thing. Two companies, through relatively recent advertising campaigns, get at the heart of the Northwest mystique with a little more humor. A SoCal/Miami Beach girl should be aware of Northwest beach culture, so check out this ad from Henry Weinhard's beer, a one-time Oregon brewery:

And Pemco Insurance has a campaign aimed at nothing but Northwest stereotypes. Socks with sandals guy, excessive recycling lady, the roadside chainsaw woodcarver ... as the slogan states, "We're a lot like you. A little different":

The couple will certainly turn a fashionable eye toward their daughter. Kim and her K-named sisters have a line for Sears; Kanye has a line for people who don't walk in the rain. People no doubt still associate Northwest fashion with flannels and fleece, but who better to outfit the little girl than The North West Clothing Co.? The Seattle-based T-shirt, hat and hoodie maker needs to start a onesie line before the girl is wearing nothing but Rob Kardashian's socks.

Through it all, we hope North West the girl grows to love Northwest the destination, even if Northwest the airline isn't around anymore to fly her here. She wouldn't be the first or last Californian to ditch all that for all this.

But she may have trouble finding us if she Googles "north west." As Buzzfeed pointed out Friday morning, the search was already returning pictures of her parents among the images of maps. Yeezus H ...

Source: http://www.today.com/entertainment/north-west-should-know-thing-or-two-about-northwest-6C10411618

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HTC Creative Director Daniel Hundt on the first-gen iPod, Leica M8 and the quandary of constant social connectivity

HTC Creative Director Daniel on the 1stgen iPod, Leica M8 and the quandry of constant social connection

Every week, a new and interesting human being tackles our decidedly geeky take on the Proustian Q&A. This is the Engadget Questionnaire.

In this week's installment of your smattering of queries, HTC's Creative Director Daniel Hundt chats up the versatile smartphone and responsible consumption. For a look at all of the responses, cozy up on the other side of the break.

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Source: http://www.engadget.com/2013/06/21/engadget-questionnaire-htc-creative-director-daniel-hundt/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Saturday, June 8, 2013

Foursquare brings a native tablet UI to Android, while iOS waits

Foursquare's first native tablet UI pops up on Android

While iOS has continued to tout its lead in native tablet apps over other platforms, there are a few cases where it lags and now Foursquare is one of them. A new update to the Android app features a new map browsing experience for tablets and large screen phones, plus improvements to the Explore feature. On the other hand, iPad users still have to deal with a stretched out version of the iPhone app for their check ins and discovery, although a fresh update there tweaks search suggestions and spellcheck in Explore. This isn't the first go round for a tablet optimized Foursquare experience on Android as the Sony Tablet S had its own app, although that was built by a third party and not fully featured.

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Source: Google Play, iTunes

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/EDs3RTwGvOE/

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Boston Marathon ?Bag Men? sue New York Post

(New York Post)

A pair of bag-carrying spectators at the Boston Marathon who were identified on the cover of the New York Post as possible suspects in the wake of the bombings have filed a defamation lawsuit against the paper, the Boston Globe reports.

A surveillance photo of Salaheddin Barhoum, a teenage student at Revere High School, and Yassine Zaimi, 24, appeared on the Post's front page on April 18 under the headline "Bag Men," hours before the FBI released photographs of Tamerlan and Dzhokhar Tsarnaev, the brothers suspected of carrying out the April 15 terror attack.

The lawsuit, filed in Suffolk Superior Court on Wednesday, accuses the News Corp.-owned tabloid of "libel, negligent infliction of emotional distress, and invasion of privacy," reports the Globe. The pair are seeking unspecified damages.

?The front page would lead a reasonable reader to believe that plaintiffs had bombs in their bags, that they were involved in causing the Boston Marathon bombing,? the complaint reads.

When the photo landed on the cover of the Post, Zaimi was called into his boss' office, where the office manager showed him a copy of the paper.

?He immediately started shaking, his mouth went dry, and he felt as though he was having a panic attack,? the complaint said.

When Barhoum was shown the paper, he "began to shake and sweat, and felt dizzy and nauseous.?

[Slideshow: How newspaper covers captured marathon bombing suspect's arrest]

"It's the worst feeling that I can possibly feel," Barhoum told ABC News on April 18.

Barhoum, a track athlete, said he wanted to run the marathon but couldn't, so he decided to watch the April 15 race instead.

The day before the Post cover came out, photos of Barhoum and Zaimi were circulated by online message boards in the frenzy to help the FBI identify the bombing suspects. Friends alerted them to the cyberhunt, and they decided to go to police to clear their names. "Authorities questioned both men, then told them they were not suspects," the Globe said.

According to ABC News, federal authorities did pass "around images of Barhoum, attempting to learn more information about him." But it's unclear whether that was before or after the Post ran with the story.

The paper was widely criticized for putting out an erroneous all points bulletin, but Post editor Col Allan was unapologetic.

"We stand by our story," Allan said in a statement. "The image was emailed to law enforcement agencies yesterday afternoon seeking information about these men, as our story reported. We did not identify them as suspects."

The Post subsequently published a separate online story reporting that Barhoum and his friend had been cleared: "The two men whose photos were being circulated internally among police have been cleared as authorities determined that neither man had any role in the Boston Marathon bombings."

El Houssein Barhoum, Salah's father, told the Washington Post last month that his family was considering a lawsuit.

?We were just scared to go outside,? he said.

Source: http://news.yahoo.com/blogs/lookout/bag-men-sue-york-post-154133149.html

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Obama: "Nobody is listening to your telephone calls" (cbsnews)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/311239015?client_source=feed&format=rss

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Friday, June 7, 2013

Obama: 'Nobody Is Listening to Your Calls' (WSJ)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/311210867?client_source=feed&format=rss

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'Thrones' author laughs at wedding reactions

TV

10 hours ago

Fans of HBO's "Game of Thrones" are still reeling from last week's Red Wedding shocker, in which the often unlucky Stark clan got a bit unluckier (and smaller), but they shouldn't look to author George R.R. Martin for sympathy.

The man behind the "Song of Ice and Fire" tales simply laughed when late night host Conan O'Brien showed a video clip jam-packed with extreme fan reactions that were captured as the episode aired.

"Of course, all of those clips were set up by people who had read the books 13 years ago and knew what was coming and wanted their friends and relatives and loved ones to do that," a clearly amused Martin said of the roundup. "I saw one of them saying, in a comment, 'Now you know why your nerdy friends were really depressed 13 years ago.'"

But what about the ones who are depressed today? As O'Brien pointed out, Martin has a way of getting "us to really care about characters, love them, think that they're central to everything" before brutally killing them. And it's tough stuff to watch.

The writer, who pens those murderous moments because that's just what he likes in a story, saves his sympathy for the actors on the show.

"There was one actress -- I won't say her name -- who, at (the season premiere) party, said 'Oh, please don't kill me! Please don't kill me! I don't want to die. I love doing this show.' And I know she does die, so? ."

Ouch.

"I felt very, very, very guilty," he admitted. "It's one thing to kill these characters when they're just people on paper. But when you actually meet the actors who portray them, and you know you're making people unemployed, it does bring up a certain amount of guilt feelings."

Find out if the author has anything else to feel guilty about when the season finale of "Game of Thrones" airs Sunday at 9 p.m. on HBO.

Source: http://www.today.com/entertainment/game-thrones-author-laughs-fan-reactions-red-wedding-6C10225159

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Wednesday, June 5, 2013

An 'extinct' frog makes a comeback in Israel

June 4, 2013 ? The first amphibian to have been officially declared extinct by the International Union for Conservation of Nature (IUCN) has been rediscovered in the north of Israel after some 60 years and turns out to be a unique "living fossil," without close relatives among other living frogs.

The Hula painted frog was catalogued within the Discoglossus group when it was first discovered in the Hula Valley of Israel in the early 1940s. The frog was thought to have disappeared following the drying up of the Hula Lake at the end of the 1950s, and was declared extinct by the IUCN in 1996. As a result, the opportunity to discover more about this species' history, biology and ecology was thought to have disappeared.

However, a team of Israeli, German and French researchers now report in the scientific journal Nature Communications on an in-depth scientific analysis of this enigmatic amphibian.

Based on new genetic analyses of rediscovered individuals and the morphologic analyses of extant and fossil bones, the conclusion is that the Hula frog differs strongly from its other living relatives, the painted frogs from northern and western Africa. Instead, the Hula frog is related to a genus of fossil frogs, Latonia, which were found over much of Europe dating back to prehistoric periods and has been considered extinct for about a million years,

The results imply that the Hula painted frog is not merely another rare species of frog, but is actually the sole representative of an ancient clade of frogs (a group with a single common ancestor).

Plans to reflood parts of the Hula Valley and restore the original swamp habitat are in place, which may allow expansion in population size and a secure future for the Hula painted frog.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/MwI6NdYAvH0/130604113437.htm

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Monday, April 29, 2013

Microchip proves tightness provokes precocious sperm release

Microchip proves tightness provokes precocious sperm release [ Back to EurekAlert! ] Public release date: 29-Apr-2013
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Contact: William Raillant-Clark
rw.raillantclark@gmail.com
514-566-3813
University of Montreal

This press release is available in French.

Sperm cell release can be triggered by tightening the grip around the delivery organ, according to a team of nano and microsystems engineers and plant biologists at the University of Montreal and Concordia University. Concordia's nanobiotech team devised a microchip that enabled the University of Montreal biologists to observe what happened when pollen tubes the sperm delivery tools used by plants tried to negotiate a microscopic obstacle course. The pollen tubes were exposed to a series of narrow, elastic openings resulting in a variety of cellular responses. When the opening was too narrow or tight, pollen tube growth stalled. However, the elongating tubes successfully penetrated slightly larger openings. Curiously, the pollen tubes burst and released the sperm cells when passing openings of a particular size relative to the pollen tube width.

The microchip was designed to imitate the mechanical challenges that the female flower tissues place in the path of the rapidly growing pollen tube on its way to the egg cell. Unlike its human counterpart, a microscopic single-cell organ undertakes sperm delivery in plants: a cylindrical protuberance formed by the male gametophyte, the pollen grain. "Similarly to elongated human cells such as neurons, the pollen tubes are tip growing cells that invade other tissues, in this case those of the female flower organs. Unlike those found in humans or other animals, the invasive ability of tip growing cells in plants remain largely unexplored. Our goal was to address this lack of knowledge using pollen tubes, whose invasive life style is the fundamental underpinning of sexual reproduction in flowering plants," said senior co-author Anja Geitmann of the University of Montreal. "Since they are encased in a stiff cellular envelope, plant cells grow and invade differently from animal cells," explained Concordia University senior co-author Muthukumaran Packirisamy. "From a mechanical point of view, the process of pollen tube elongation is similar to that of a balloon catheter used for angioplasty - forces are generated based on the principle of a hydroskeleton, or fluid under pressure. We designed microchannels through which the pollen tubes had to forcefully squeeze in order to continue their elongation."

Microsystems technology was required to undertake this experiment due to the tiny size of pollen tubes and the consequently minute amount of force they exert to accomplish penetration. The pollen tube requires not only an invasive force to overcome the mechanical resistance of the surrounding tissue, but also the protection of the contents that is to be transported, the sperm cells, of which there are exactly two in each tube. It is crucial that the pollen tube remains tubular while winding its way through the pistil, since kinks and collapses of this catheter-like organ prevent the passage of the sperm cells, similar to a blockage in a twisted garden hose. A typical pollen tube can become many centimeters long but is only between 5 and 20 micrometres wide. By way of comparison, a human hair is typically 100 micrometres thick. "To fit the dimensions of this cell, we had to design the microchip with microscopic channels and obstacles that are narrower than the pollen tubes. We used high resolution soft and direct write lithography techniques to produce this micron-sized obstacle course. Furthermore, measuring the pressure that pollen tubes exert requires materials that are just the right consistency not too hard and not too soft. We chose an elastic polymer material, and as the tubes deformed the material at some levels of tightness, we can be certain that the softness was just right. Mechanical modeling allowed us to calculate the forces exerted by these cells. Lab-on-a-Chip (LOC) technology allows us to assess cellular behavior much better than the conventional Petri dish," Packirisamy said.

Sexual reproduction in plants is in many ways analogous to human biology. "In order to find its path to the ovule and the egg cell, the pollen tube has to invade a series of female tissues in the receptive flower," Geitmann explained. "The male and the female organs continuously communicate during the process. The female aids the process by lubricating the path, but the male exerts significant force to overcome any residual resistance." The pollen tube must penetrate through a central canal that connects the stigma, or pollen landing platform, to the ovary, the organ that houses the ovules. Upon reaching the ovary, it then passes onto the internal surface of the placenta, finds and enters the opening in the ovule, and finally bursts open when connecting with the egg cell, enabling its fertilization by one of the two sperm cells it delivers. The other sperm cell fertilizes another cell of the female gametophyte to give rise to a tissue that nourishes the growing embryo.

How the timely discharge of the sperm cells is triggered in plants has essentially been unknown. The control of this process is crucial for successful fertilization and seed set, since plant sperm is not motile and must therefore be delivered precisely to its target. A precocious discharge (before the pollen tube reaches the ovule) will not allow the sperm cells to reach the egg, whereas on the other hand, a failure to discharge equally precludes fertilization. "Our findings show that a tight grip around the tube does result in sperm release. This illustrates that plant cells perceive and respond to mechanical stimuli," Geitmann said. "However, the particularities of the cellular responses we observed suggest that other factors, such as protein-based signals, are likely to be in play." The researchers believe that these particularities and the mechanisms that control pollen tube diameter and growth behavior warrant further research. "We're still not sure exactly what causes the sperm cell release from the pollen tube in vivo, but a mechanical trigger might be part of the signaling mechanism," Packirisamy said.

###

About this study:

Amir Sanati Nezhad, Mahsa Naghavi, Muthukumaran Packirisamy, Rama Bhat and Anja Geitmann published "Quantification of cellular penetrative forces using Lab-on-a-Chip technology and finite element modeling" in the Proceedings of the National Academy of Sciences. This study received funding from Fonds de recherche du Qubec Nature et Technologies. Mechanical modeling expertise was contributed by co-author Professor Rama Bhat, Concordia University. The University of Montreal is officially known as Universit de Montral.


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Microchip proves tightness provokes precocious sperm release [ Back to EurekAlert! ] Public release date: 29-Apr-2013
[ | E-mail | Share Share ]

Contact: William Raillant-Clark
rw.raillantclark@gmail.com
514-566-3813
University of Montreal

This press release is available in French.

Sperm cell release can be triggered by tightening the grip around the delivery organ, according to a team of nano and microsystems engineers and plant biologists at the University of Montreal and Concordia University. Concordia's nanobiotech team devised a microchip that enabled the University of Montreal biologists to observe what happened when pollen tubes the sperm delivery tools used by plants tried to negotiate a microscopic obstacle course. The pollen tubes were exposed to a series of narrow, elastic openings resulting in a variety of cellular responses. When the opening was too narrow or tight, pollen tube growth stalled. However, the elongating tubes successfully penetrated slightly larger openings. Curiously, the pollen tubes burst and released the sperm cells when passing openings of a particular size relative to the pollen tube width.

The microchip was designed to imitate the mechanical challenges that the female flower tissues place in the path of the rapidly growing pollen tube on its way to the egg cell. Unlike its human counterpart, a microscopic single-cell organ undertakes sperm delivery in plants: a cylindrical protuberance formed by the male gametophyte, the pollen grain. "Similarly to elongated human cells such as neurons, the pollen tubes are tip growing cells that invade other tissues, in this case those of the female flower organs. Unlike those found in humans or other animals, the invasive ability of tip growing cells in plants remain largely unexplored. Our goal was to address this lack of knowledge using pollen tubes, whose invasive life style is the fundamental underpinning of sexual reproduction in flowering plants," said senior co-author Anja Geitmann of the University of Montreal. "Since they are encased in a stiff cellular envelope, plant cells grow and invade differently from animal cells," explained Concordia University senior co-author Muthukumaran Packirisamy. "From a mechanical point of view, the process of pollen tube elongation is similar to that of a balloon catheter used for angioplasty - forces are generated based on the principle of a hydroskeleton, or fluid under pressure. We designed microchannels through which the pollen tubes had to forcefully squeeze in order to continue their elongation."

Microsystems technology was required to undertake this experiment due to the tiny size of pollen tubes and the consequently minute amount of force they exert to accomplish penetration. The pollen tube requires not only an invasive force to overcome the mechanical resistance of the surrounding tissue, but also the protection of the contents that is to be transported, the sperm cells, of which there are exactly two in each tube. It is crucial that the pollen tube remains tubular while winding its way through the pistil, since kinks and collapses of this catheter-like organ prevent the passage of the sperm cells, similar to a blockage in a twisted garden hose. A typical pollen tube can become many centimeters long but is only between 5 and 20 micrometres wide. By way of comparison, a human hair is typically 100 micrometres thick. "To fit the dimensions of this cell, we had to design the microchip with microscopic channels and obstacles that are narrower than the pollen tubes. We used high resolution soft and direct write lithography techniques to produce this micron-sized obstacle course. Furthermore, measuring the pressure that pollen tubes exert requires materials that are just the right consistency not too hard and not too soft. We chose an elastic polymer material, and as the tubes deformed the material at some levels of tightness, we can be certain that the softness was just right. Mechanical modeling allowed us to calculate the forces exerted by these cells. Lab-on-a-Chip (LOC) technology allows us to assess cellular behavior much better than the conventional Petri dish," Packirisamy said.

Sexual reproduction in plants is in many ways analogous to human biology. "In order to find its path to the ovule and the egg cell, the pollen tube has to invade a series of female tissues in the receptive flower," Geitmann explained. "The male and the female organs continuously communicate during the process. The female aids the process by lubricating the path, but the male exerts significant force to overcome any residual resistance." The pollen tube must penetrate through a central canal that connects the stigma, or pollen landing platform, to the ovary, the organ that houses the ovules. Upon reaching the ovary, it then passes onto the internal surface of the placenta, finds and enters the opening in the ovule, and finally bursts open when connecting with the egg cell, enabling its fertilization by one of the two sperm cells it delivers. The other sperm cell fertilizes another cell of the female gametophyte to give rise to a tissue that nourishes the growing embryo.

How the timely discharge of the sperm cells is triggered in plants has essentially been unknown. The control of this process is crucial for successful fertilization and seed set, since plant sperm is not motile and must therefore be delivered precisely to its target. A precocious discharge (before the pollen tube reaches the ovule) will not allow the sperm cells to reach the egg, whereas on the other hand, a failure to discharge equally precludes fertilization. "Our findings show that a tight grip around the tube does result in sperm release. This illustrates that plant cells perceive and respond to mechanical stimuli," Geitmann said. "However, the particularities of the cellular responses we observed suggest that other factors, such as protein-based signals, are likely to be in play." The researchers believe that these particularities and the mechanisms that control pollen tube diameter and growth behavior warrant further research. "We're still not sure exactly what causes the sperm cell release from the pollen tube in vivo, but a mechanical trigger might be part of the signaling mechanism," Packirisamy said.

###

About this study:

Amir Sanati Nezhad, Mahsa Naghavi, Muthukumaran Packirisamy, Rama Bhat and Anja Geitmann published "Quantification of cellular penetrative forces using Lab-on-a-Chip technology and finite element modeling" in the Proceedings of the National Academy of Sciences. This study received funding from Fonds de recherche du Qubec Nature et Technologies. Mechanical modeling expertise was contributed by co-author Professor Rama Bhat, Concordia University. The University of Montreal is officially known as Universit de Montral.


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Source: http://www.eurekalert.org/pub_releases/2013-04/uom-mpt042413.php

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Syrian premier escapes bomb attack in Damascus

This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says the country's prime minister has escaped an assassination attempt when a bomb went off near his convoy. The TV says Prime Minister Wael al-Halqi was unhurt in the attack in the capital's western neighborhood of Mazzeh. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says the country's prime minister has escaped an assassination attempt when a bomb went off near his convoy. The TV says Prime Minister Wael al-Halqi was unhurt in the attack in the capital's western neighborhood of Mazzeh. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says the country's prime minister has escaped an assassination attempt when a bomb went off near his convoy. The TV says Prime Minister Wael al-Halqi was unhurt in the attack in the capital's western neighborhood of Mazzeh. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says the country's prime minister has escaped an assassination attempt when a bomb went off near his convoy. Syrian TV says Prime Minister Wael al-Halqi was unhurt in the attack in the capital's western neighborhood of Mazzeh. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows a Syrian man reacts after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says the country's prime minister has escaped an assassination attempt when a bomb went off near his convoy. Syrian TV says Prime Minister Wael al-Halqi was unhurt in the attack. (AP Photo/SANA)

EDS NOTE: GRAPHIC CONTENT -- This photo released by the Syrian official news agency SANA, shows Syrians carrying a charred body after a car bomb exploded in the capital's western neighborhood of Mazzeh, in Damascus, Syria, Monday, April. 29, 2013. State-run Syrian TV says Prime Minister Wael al-Halqir has escaped unhurt in an assassination attempt when a bomb went off near his convoy. (AP Photo/SANA)

(AP) ? Syria's prime minister escaped an assassination attempt Monday when a bomb went off near his convoy in Damascus, state media reported, the latest attack targeting a top official in President Bashar Assad's regime.

Prime Minister Wael al-Halqi was unhurt in the bombing in the capital's western neighborhood of Mazzeh, state TV said. The TV showed footage of heavily damaged cars and debris in the area as firefighters fought to extinguish a large blaze set off by the explosion.

The state SANA news agency said one person was killed and several were wounded in the blast.

The daring attack in the upscale neighborhood, which is home to many embassies and government officials, was another blow to the regime, exposing its vulnerability in the very seat of Assad's powerbase.

Syria's conflict started with largely peaceful anti-government protests in March 2011 but eventually turned into a civil war that has so far killed more than 70,000 people, according to the United Nations.

A Syrian government official told The Associated Press that an improvised explosive device was placed under a car that was parked in the area and was detonated as al-Halqi's car drove by. The official spoke on condition of anonymity because he was not authorized to speak to the media.

The state-run Al-Ikhbariya station said al-Halqi went into a regular weekly meeting with an economic committee straight after the bombing and showed him sitting around a table in a room with several other officials.

The TV said it was showing the video as a proof that al-Halqi was not hurt. But the prime minister's comments after the meeting did not refer to Monday's blast and he was not asked about it by reporters, leaving doubts as to whether the footage was filmed before or after the bombing.

Al-Halqi condemned the blast, SANA said, adding that the attempt exposes how armed groups "are bankrupt" after the latest advances made by Syrian troops around the country.

The Britain-based Syrian Observatory for Human Rights said Monday's bombing killed al-Halqi's bodyguard and that one of his drivers was in critical condition. The group relies on a network of activist around the country.

The brazen attack in the highly secure Mazzeh neighborhood took place only about 100 meters (yards) from the residence of the Swiss ambassador. The posh area is also home to a major military air base, and security forces sealed it off shortly after the blast, allowing only pedestrians to come close.

At the scene of the bombing, damaged cars were surrounded by debris, their seats soaked with blood. A blackened shell of a school bus was left standing. A man told state TV that none of the students on board were hurt because the explosion went off shortly after they had left the bus and headed into the school.

The attack was not the first targeting a high official in the Syrian capital over the past year.

On July 18, a blast at the Syrian national security building in Damascus during a meeting of Cabinet ministers killed top four officials, including the defense minister and his deputy, who was Assad's brother-in-law. That attack also wounded the interior minister.

In December, a car bomb targeted the Interior Ministry in Damascus, killing several people and wounding more than 20, including Interior Minister Mohammed al-Shaar. Initially, Syrian state media said al-Shaar was not hurt in the Dec. 12 blast. News of his wounds emerged a week later, after he was brought to neighboring Lebanon for medical treatment for a serious back injury.

Earlier in April, Ali Ballan, head of public relations at the Ministry of Social Affairs and a member of Syria's relief agency, was shot dead while dinning in a restaurant in Mazzeh.

There was no immediate claim of responsibility for Monday's attack.

Massive bombings like the one that struck the prime minister's convoy have been a trademark of Islamic radicals fighting alongside the Syrian rebels, raising concerns about the extremists' role in Syria's civil war.

Al-Halqi, a senior member of Assad's ruling Baath party, took office last year after his predecessor, Riad Hijab, defected to Jordan. Al-Halqi was Syria's health minister before taking the post. He is a member of Assad's ruling Baath party and hails from the southern city of Daraa, the birthplace of the Syrian uprising.

Elsewhere in Syria, the Observatory reported fighting Monday near the Damascus International Airport to the south of the capital. The group said there were also clashes in the northern neighborhood of Barzeh and shelling of the Palestinian refugee camp of Yarmouk, south of Damacus.

The Observatory and another activist group, the Local Coordination Committees, reported clashes and air raids around the military helicopter base of Mannagh near the border with Turkey in the northern province of Aleppo. On Sunday, the Aleppo Media Center said that the rebels have seized 60 percent of the Mannagh air base.

Both groups also reported clashes and shelling Monday in the northwestern province of Idlib and the central region of Homs.

___

Associated Press writers Barbara Surk and Bassem Mroue contributed to this report from Beirut.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-29-Syria/id-ef082db9a6c449c0b65c2cadd10092de

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Bombing shifts Mass. Senate race before primaries

BOSTON (AP) ? Even before the explosions, polling suggested that Massachusetts voters weren't excited about the looming special election to replace former U.S. Sen. John Kerry.

But in the days after bombs ripped through the Boston Marathon's crowded streets, politics were all but forgotten as authorities launched an unprecedented manhunt and a region grappled with terror. It didn't matter that competitive primary contests were 15 days away; everything was put on hold.

"There are things that are more important than campaigning and that horrific event was clearly one of them," said U.S. Rep. Ed Markey, who is competing against U.S. Rep. Stephen Lynch for the Democratic nomination to replace Kerry, now the secretary of state.

After suspending political activities for roughly a week, the candidates have been forced to walk a delicate balance as they engage voters ahead of Tuesday's Republican and Democratic primaries. They have largely avoided the site of the attack out of sensitivity for victims, but some have tweaked campaign advertising to address the bombing, highlighted their national security credentials and tried to use the sudden focus on terrorism to shift the direction of the race.

"It completely changed the landscape," Lynch aide Scott Ferson said of the bombing.

Indeed, a campaign once dominated by debates about the environment, health care and women's rights has become more focused on enemy combatants, Miranda rights and counterterrorism agencies. Some candidates welcomed the shift.

On the Democratic side, Lynch has seized on national security in recent days to attack Markey, thought to be the front-runner. One of the most memorable moments in last week's Democratic debate, just a week after the bombing, focused on support for federal security efforts

"Unlike my colleague Mr. Markey, I've actually voted for the Department of Homeland Security appropriations bills," Lynch charged.

Markey responded: "He's taking a page right out of the Karl Rove swift boat playbook, and it's very sad, especially just one week after what just happened in Boston, Cambridge and Watertown."

Through Tuesday's primary election, Markey outspent Lynch on television advertising $1.7 million to $1.2 million, according to advertising figures obtained by The Associated Press. But only Lynch focused on the bombings in a television ad that blanketed the state last week, while Markey focused on traditional Democratic priorities such as women's reproductive rights.

"We hold in our hearts those we lost, but we will get through this together and work toward a brighter day," Lynch says in the campaign ad.

But Lynch was forced to distance himself last week from a so-called robo-call made on his behalf by the leader of an ironworkers' union, who mentions the bombings while encouraging voters to support someone who "understands the day-to-day problems facing working families." It was an awkward moment for the Lynch campaign, which called on the group to stop the calls.

But it's unclear how many people were paying attention.

"The bombings basically sucked all the air out of the room," said Steve Koczela, president of MassINC Polling Group, which found last month that more than 40 percent of likely Democratic voters and nearly 50 percent of likely Republican voters hadn't settled on a candidate.

"It just doesn't seem like ? even as of the last poll ? people were really paying attention to who was running," Koczela continued. "There's room for any of the candidates to make a move."

On the Republican side in particular, the recent violence shifted the contours of the contest.

GOP candidate Gabriel Gomez, a former Navy SEAL, finished running the marathon minutes before the bombs exploded along the finish line, killing three and injuring more than 260.

Like other candidates, Gomez immediately pulled television ads off the air and suspended campaign activities. He said he was focused on being respectful as he eased back into campaigning the following weekend.

"We can't let the terrorists win and completely suspend what is fundamental right in the United States," Gomez said.

He charged that President Barack Obama's administration should have designated 19-year-old suspect Dzhohkar Tsarnaev an "enemy combatant" and tried him outside the traditional criminal justice system.

Another GOP candidate, Mike Sullivan, says the federal government should have denied Tsarnaev his Miranda rights, tried him as an enemy combatant and revoked his U.S. citizenship.

"Our first concern must always be preventing future terrorist acts against our people," said Sullivan, a former U.S. attorney whose campaign has been reminding people that he previously led the prosecution of shoe bomber Richard Reid.

Republican candidate Dan Winslow, a former judge and chief legal counsel under former Gov. Mitt Romney, said the entire GOP field has experience with national security.

"We've got a Navy SEAL, a former prosecutor and a former judge all in the field for Republicans," Winslow said. "I think we all have our own credentials. The key is, Who's got the better ideas? Who's got the better electability in June?"

The key may also be which candidate can get his supporters to get to the polls as the bombing continues to dominate attention in Massachusetts. State officials were already predicting a low turnout, likely less than 20 percent of eligible voters, even before the attack.

Wendy Becker, 45, of Newton, was among the thousands who visited the bomb site in Copley Square late last week. A registered voter, she said she didn't know the primaries were happening so soon.

"I didn't even know it was Tuesday and haven't cared," she said, noting that her little brother and brother-in-law ran in the marathon. She's been glued to the television coverage of the aftermath ever since.

The general election, featuring the primary winners, is scheduled for June 25.

___

Associated Press writer Steve LeBlanc contributed to this report.

Source: http://news.yahoo.com/bombing-shifts-mass-senate-race-primaries-170401370.html

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Two Meteorites Discovered In Antarctica May Be From The Same Supernova

There's nothing more fascinating or TV special-worthy than twins separated at birth. Whether they're reunited at 15 or 50 it's safe to say that there'll be some eerily similar food preferences and a whole lot of crying. But what about two chemically identical grains of silica that haven't seen each other for more than 4.6 billion years? More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/bzvphgpRnU0/two-meteorites-discovered-in-antarctica-may-be-from-the-same-supernova

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Friday, April 26, 2013

AmaWaterways unveils 2014 Africa Safaris & Wildlife Cruise brochure

AmaWaterways proudly announces the release of its new 2014 Africa Safaris & Wildlife Cruise brochure. The brochure provides complete details about AmaWaterways? one-of-a-kind program in Africa, with four different land safari itineraries ? Discover Africa, Stars of South Africa, Rivers & Rails of Africa and Golden Trails of East Africa ? all which include a wildlife river safari on Botswana?s Chobe River. AmaWaterways is the only river cruise company operating in Africa that offers both river and land-based safari programs.

Guests aboard AmaWaterways? wildlife river cruise will enjoy a 4-night stay on the 28-passengerZambezi Queen. As a modern ?eco-ship,? the Zambezi Queen offers deluxe accommodations, fine dining and floor-to-ceiling panoramic windows, making it an excellent vantage point for game-viewing. Following the cruise, guests will spend two full days at the legendary Victoria Falls.

?Africa is a truly magical destination, and our goal was to convey some of the ambiance of a classic African safari with this beautiful brochure,? said AmaWaterways? Executive Vice President and Co-Owner Kristin Karst. ?Our African itineraries offer our guests up-close, unhurried and unforgettable wildlife viewing opportunities, as well as unique cultural encounters and other in-depth, authentic travel experiences.?

AmaWaterways? cruise-and-land safari programs include the 12-day Discover Africa, the 15-day Rivers & Rails of Africa, the 16-day Stars of South Africa and the 18-day Golden Trails of East Africa. New enhancements to the 2014 program include the ?Rivers & Rails of Africa? itinerary option, which features two nights aboard the Rovos Rail luxury train, as well as exclusive use of some of the most incredible accommodations in Africa (such as Singita Sweni Lodge and Singita Sabora Tented Camp, both of which have been ranked among the world?s ?Top 10 Hotels? by Travel + Leisure). Other program highlights include city tours, wine tastings, morning and afternoon game drives, an excursion in a traditional dugout canoe, private game reserve picnics, a traditional African boma dinner onshore, a visit with local villagers and a guided tour of Victoria Falls.

Recommended

Source: http://www.breakingtravelnews.com/news/article/amawaterways-unveils-2014-africa-safaris-wildlife-cruise-brochure/

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"Chief Porn Identification Officer:" The Best Job You'll Never Have

If you could do anything—anything—for a living what would it be? Well that's dumb; it would be "looking at porn." And though you may not be so lucky, someone working for China will be, boasting the prestigious title of Chief Porn Identification Officer. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/5FrLPOBZtqE/chief-porn-identification-officer-the-best-job-youll-never-have

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